YURI M. LVOV

[image]

 

Current Position Professor, Tolbert Pipes Endowed Chair on Micro and Nanosystems, Institute for Micromanufacturing, Louisiana Tech University, 911 Hergot Ave., Ruston, LA 71272; office (318)257-5144, ylvov@latech.edu

Education

 

Honors/Awards

● Award Certificate from American Chemical Society for organization of Symposium “Nanoassemblies: From Fundamentals to Applications,” 236th ACS National Meeting in Philadelphia, August 2008

● US National 2007 Best of Small Tech Award in the category Innovator of the Year. Best of Small Tech Awards recognize achievements in micro and nanotechnology.

●Annual Award: 2006 Outstanding Louisiana Researcher in Emerging Technologies

●Medal for Best Research Achievements from Engineering Department, LaTech, 2005

●Tolbert Pipes Eminent Endowed Chair on Micro and Nanosystem, 2004.

●In 2004, US Institute of Scientific Information ranked our article in “Langmuir,” v.9, p.481, among three most cited papers on molecular self-assembly (citations: 430), and another my paper on protein architecture in the Journal of American Chemical Society, 1995, v.117, p.6177 was cited 730 times which makes it #4 most cited chemistry paper in with Japanese co-authors. A total citation of my papers on nanoassembly is above 7,000 and my H-index is 40.

●Award Certificate from American Chemical Society for organization of “Smart Nanoassemblies” Symposium at 226th ACS National Meeting in New York, September 2003.

●Royal Chemical Society Publication Award, 1999, UK;

●Alexander von Humboldt Fellowship, 1991-1993, Germany;

●Awarded with Doctor of Science in Physics from Moscow State University, 1990, Russia.

 

Experience

2004-now Professor of Chemistry, Tolbert Pipes Eminent Endowed Chair on Micro and Nanosystems, Institute for Micromanufacturing, LaTech; Affiliated Faculty at Biomedical Engineering Department, Louisiana Tech University, Ruston, President of Nano Pulp and Paper, LLC

1999-2003 Associate Professor, Institute for Micromanufacturing and Chemistry Program, Affiliated Faculty in the Physics and Biomedical Engineering Departments, Louisiana Tech University, Ruston, LA.

1998-1999 Research Associate Professor, Center Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington DC.

    1. Research Associate and Adjunct Professor, Chemistry Department, University of Connecticut, Storrs, CT.

    2. Staff Researcher, Research & Development Corporation, Japan Science Agency, Fukuoka.

    3. Alexander von Humboldt Fellowship, Mainz University, Institute of Physical Chemistry, Germany.

    4. Senior Researcher, Thin film group leader, Institute of Crystallography, Russian Academy of Sciences, Moscow.

Temporary ●Visiting Scientist, Materials Directorate, Wright - Patterson Air Force Base, Dayton, OH,

Positions: September 1997. ●Visiting Professor, Molecular Electronics Center, Durham University, UK, April-May 2000. ●Adjunct Professor in Pharmaceutics in the Department of Pharmaceutical Sciences at University of Louisiana in Monroe, 2003-2006. ●Visiting scholar (sabbatical leave), Max Planck Institute for Colloids and Interfaces, Potsdam, Germany, August – December 2007.

 

Scientific/Professional Societies

American Chemical Society, since 1994. Alexander von Humboldt Foundation, since 1991.

TAPPI (Technical Association for Pulp and Paper Industry) member since 2004 

Research grants and contracts - my group funding exceeded $ 5 mln from more than $ 12 million of my total (with co-PIs) grants’ budget

 

  1. “Center for Advanced Materials and Nanotechnology in AMRI at the University of New Orleans,” PI (co-PI: C. O’Connor), post-KSFI, BoR, my part $550K from total $ 3 mln, 2007-2012

  2. “Nanotechnology for Pulp and Paper Industry: Layer-by-Layer Polyelectrolyte Coating,” PI, LA Board of Regent Industry Ties Program, $180,000; July 1, 2005 – June 30, 2009.

  3. “An Efficient Method for Simulating Diffusion Inside Nanotubes for Drug Delivery Systems” co-PI (PI: D. Liu), $83,800 BoR-RCS, July 2007-June 2010

  4. ”Clay Nanotubes for Controlled Release of Anticorrosion Agents,” PI, BoR-PFUND, $10,000; April 2008-May 2009.

  5. “Nanoassembly: from Fundamentals to Applications,” Funding for International Symposium, Y. Lvov - PI and Symposium Chair, $3,600 grant from ACS Petroleum Research Foundation, Philadelphia, Aug 1 –Sept 30, 2008

 

Successfully Concluded:

  1. “Research and Education: Increasing Student Participation in Research at Internationally Recognized User Facilities,” co-PI, NSF, $300,000; Sept 2005- August 2008.

  2. “Enhancement of Educational and Research Infrastructure for Nanosystems Engineering and Molecular Science and Nanotechnology Curricula” PI, BoR LEQSF(2007-08)-ENH-TR-45, $69,000, July 2007- August 2008

  3. “Understanding the Local Atomic-Level Effect of Dopant in Complex Metal Hydrides, USING Synchrotron X-Ray Absorption Spectroscopy” co-PI, DoE, $300,000 Sept 2005-August 2008

  4. “Stronger Paper with Better Recycling through Nanoassembly,” PI, USDA-SBIR, $80,000 May 2007-Apr 2008.

  5. “Theoretical, Numerical and Experimental Studies of an Intermediate-layer Lithography Approach,” NSF, co-PI (PI: C. Liu), $220,000, June 2007-March 2008

  6. “Protein Drug Microencapsulation,” Epic Therapeutic / Baxter Corporation contract, PI, $340,000; May 2004 - Nov 2007

  7. “Modification of Corneal Tissue Engineered Scaffolds to Promote Epithelialization,” $50,000, PIs: Y. Lvov and J. Jacob, Mentee Faculty: S. Sit; BoR, 2006-Dec 2007.

  8. “Nanoengineered Shells for Encapsulation and Controlled Release,” PI, budget $901,000; NSF-NIRT 0210298, Sept 2002-Aug 2007.

  9. “Planning for the Biomedical Nanosystems IGERT Program,” co-PI (PI: K. Varahramyan), BoR, $10,000, July 2006- March 2007.

  10. “Composite Material of Clay Nanotubes and Cellulose Microfibers,” PI, $5,000, NASA-LURA, Sept 06- Aug 2007

  11. “LbL-Nanoassembly for Pulp Treatment,” SAPPI Fine Paper Corporation contract, PI, $120,000; Jan 2006 - Nov 2006

  12. “Acquisition of Field Emission Scanning Electron Microscope,” co-PI, NSF, $523,000, Sept 2005 - Sept 2006

  13. “Nanoscale Biotechnology: Materials, Methods, Devices,” co-PI, Louisiana Governor Biotechnology Initiative, $1,950,000 Jan 2005- December 2006.

  14. “Smart Nano Pulp and Paper,” PI, DARPA/NAVY through internal IfM grant, March 2005-August 2006, my part $64,000

  15. “Teaching Nanosystem Engineering to Early College Students with Active Learning Experience,” NSF-NUE, co-PI, June 2004 – June 2006, $100,000.

  16. “Fluorescent Glucose Sensors from Polyion Shells,” co-PI, total budget $1,329,000; NIH-1RO1 EB00739-01; Sept 02-Aug 06.

  17. “Self-Assembly of Microshells with Nanoorganized Walls for Drug Encapsulation”, PI, Louisiana Board of Regents 2002/05-RDA19, budget $130,000; July 2002-June 2005.

  18. “Nanoparticle Technology for DNA-Repair Enzyme Delivery,” co-PI, total budget of $1,458,000; Dec 2001- January 2005, NASA: NAS2-02059.

  19. “Micro / Nanodevices and Systems for Biochemical Sensors and Signaling,” co-PI, total budget of $2,920,000. June 2001 – December 2004. NSF-LEQSF 0092001.

  20. “Biosystems Nanomanufacturing Research and Development Center” Louisiana BoR, PI, $50,000; Sept 2003-March 2005.

  21. “Optimization of polyion coating for specific adsorption of progesterone and estradiol,” PI, budget $120,000, contract with Ciba-Vision Corporation, March 2003-June 2004.

  22. “Nanoconstruction on Microtemplates,” PI, $70,000, Sept 2000 – December 2002, Source of support: American Chemical Society-Petroleum Fund: 36066-AC5.

  23. “Layer-by-Layer Immobilization of Organophosphorus Anhydrase,” PI, contract 01-P-1567, Naval Research Lab, Office of Naval Research, PI, $50,000; July 2001- April 2002.

  24. “Development of Microchip for Sensing Nerve Agents Based on Enzyme Nanoassembly,” CEnIT-LaTech, PI, $ 29,000, Dec 2001- Sept 2002.

  25. “Implementation of a Device for Assessing Dosage for Platelet Glycoprotein Inhibitors,” PI, $32,000; LaTech, CEnIT, January 2002-Dec 2002.

  26. “Nano-Fabrication of Artificial Red Blood Cells,” co-PI, $8,000 Louisiana Space Consortium (NASA Space Grant Program for Undergraduates), Sep 2001- Aug 2002.

  27. “Smart Nano/Assemblies (to organize Polymer Materials Science and Engineering Symposium at 226th ACS Meeting)”, PI, Petroleum Research Foundation, March – December 2003, $7,600.

 

Pending

  1. “Layer-by-layer Nanocarriers for Highly Efficient Solubilization of Insoluble Drugs,” co-PIs Y. Lvov, V.Torchilin, NIH, $1,500,000; July 1, 2009 - June 30, 2013

  2. “IGERT Project in Multi-Scale Integration of Biomimetic Systems,” co-PI (PI: M. Decoster), NSF, $3mln, 2009-2012.

 

11 Patents (issued or pending)

  1. “Multiple Layered Functional Thin Films,” M. Onda, Y. Lvov, K. Ariga, T. Kunitake February 1, 2000, US patent 6020175.

  2. “Preparation of Immobilized Protein Ultrathin Film Reactor and Chemical Reaction by Using Immobilized Protein Film Reactor,” M. Onda, Y. Lvov, K. Ariga, T. Kunitake, August 22, 2000, US Patent 6107084

  3. “Fluorescent Sensors Based on Encapsulation of Indicator Dyes with Polyion Shells,” M. McShane, Y. Lvov. US Patent 10/360,328 from February 7, 2003.

  4. “Lithographically-Based Approach to Pattern Layer-by-Layer Nano-assembled Thin Films for Microelectronics / MEMS Devices,” Inventors: T. Cui, Y. Lvov, F. Hua. US patent 7,090,783 B1 from Aug 15, 2006

  5. “Preparation of Protein Ultrathin Films Using Alternate Adsorption Technique,” T. Kunitake, K. Ariga, Y. Lvov; September 24, 1996, Japanese patent 8-245815.

  6. “Sustained Drug Release from Nanoorganized Polyion Microcapsules,” H. Ai, S. Jones, M. DeVilliers, Y. Lvov, filed on 8-Jan-05, US patent application # 60/535,664.

  7. “Paper and pulp nano/coating by multistep adsorption of oppositely charged linear polyions, nanoparticles, proteins and DNA,” inventors: Y. Lvov, G. Grozdits, filed March 15, 2005, application number # 60/661,640

  8. “Polyion Layer-by-Layer Coating of Microparticles,” J. Rashba-Step, T. Scott, R. Darvari, Y. Lvov, T. Shutava, April 27, 2006, #20060260777 (together with Baxter Corporation)

 

  1. "Targeted Layer by Layer Engineered Nanoparticles for Sustained Release of Small Molecules,” inventors: C. Leuschner, C. Kumar, Y. Lvov, US patent application, March 31, 2006 #60/787,849 (together with LSU)

  2. “Stable Nano-Colloids of Poorly Water Soluble Drugs,” Y. Lvov, A. Agarwal, V. Torchilin, US patent application together with Northeastern University, Boston, July 16, 2008, no 60/959,728

  3. ”Method for the Manufacture of Smart Paper and Smart Wood Microfibers,” M. Agarwal, Y. Lvov, K. Varahramyan, US patent application from October 30, 2007 # 11/928,626

Disclosures to LaTech and Patent Applications - Sixteen disclosures were submitted to LaTech

Publications

  1. Articles Total – 170 articles published in peer reviewed journals; 30 most important articles are given below:

  1. A. Agarwal, Y. Lvov, R. Sawant, V. Torchilin, J. Controlled Release, v.7, 788-796, 2008, “Stable Nanocolloids of Poorly Soluble Drugs with High Drug Content Prepared Using Sonic Layer-by-Layer Technology.”

  2. Y. Lvov, D. Shchukin, H. Moehwald, R. Price, ACS Nano, v.2, 567-572, 2008, “Clay Nanotubes for Controlled Release of Protective Agents” – feature/ perspective paper

  3. N. Veerabadran, R. Price, Y. Lvov, NANO Journal, v.2, 215-222, 2007 “Clay Nanotubules for Drug Encapsulation and Sustained Release”

  4. V. Kamineni, Y. Lvov, T. Dobbins, Langmuir, v. 23, 7423-7427, 2007, “Layer-by-Layer Nanoassembly of Polyelectrolytes Performed Using Formamide as the Working Medium”

  5. M. Agarwal, Y. Lvov, K. Varahramyan, Nanotechnology, v.17, 5319-5325, 2006, “Conductive Wood Microfibers for Smart Paper Through Layer-by-Layer Nanocoating”

  6. Y. Lvov, Z. Zheng, Z. Lu, S. Eadula, G. Grozdits, Nordic Pulp and Paper Research J., v.21, 552-559, 2006, “Layer-by-Layer Nanocoating of Mill Broken Fibers for Improved Paper”

  7. T. Shutava, D. Kommireddy, Y. Lvov, J. Am. Chem. Soc., 2006, v.128, 9926-9934, “Polyelectrolyte / Enzyme Multilayer As Functional Protective Nano/barrier in Oxidizing Media”

  8. N. Li, D. Kommireddy, Y. Lvov, W. Liebenberg, L. Tiedt, M. De Villiers J. Nanoscience Nanotechnology, v.6, 3252-3260, 2006, “Nanoparticle Multilayers: Surface Modification of Photosensitive Drug Microparticles for Increased Stability and In Vitro Bioavailability”

  9. Z. Zheng, J. McDonald, R. Khillan, T. Shutava, G. Grozdits, Y. Lvov, J. Nanoscience Nanotechnology, v.6, 624-632, 2006, “Layer-by-Layer Nanocoating of Lignocellulose Fibers for Enhanced Paper Properties”

  10. N. Pargaonkar, Y. Lvov, N. Li, M. de Villiers, Pharmaceutical Res. J., v.22, 826-835, 2005, “Controlled Release of Dexamethasone from Microcapsules Produced by Polyelectrolyte Layer-by-Layer Nanoassembly.”

  11. D. Kommireddy, A. Patel, T. Shutava, D. Mills, Y. Lvov, J. Nanoscience Nanotechnology, v.5, 1081-1087, 2005, “Layer-by-Layer Assembly of TiO2 Nanoparticle for Stable Hydrophilic Biocompatible Coating”

  12. D. Shchukin, R. Price, G. Sukhorukov, Y. Lvov, Small (Nano- Micro), v.1, 510-513, 2005, “Biomimetic Synthesis of Vaterite in the Interior of Clay Nanotubules”

  13. D. Shchukin, A. Patel, G. Sukhorukov, Y. Lvov, J. Am. Chem. Society, 2004, v.126, 3374-3376, “Nanoassembly of Biodegradable Microcapsules for DNA Encasing”

  14. T. Cui, F. Hua, Y. Lvov, IEEE Electronic Devices, 2004, v.51, 503-507 “Field Effect Transistor Fabricated by Electrostatic Layer-by-Layer Nanoassembly”

  15. F. Hua, T. Cui, Y. Lvov, Nano Letter, 2004, v.4, 878-882, “Ultrathin Cantilevers Based on Polymer-Ceramic Nanocomposite Assembled through Layer-by-Layer Adsorption”

  16. D. Shchukin, D. Kommireddy, T. Cui, G. Sukhorukov, Y. Lvov, Advanced Materials, 2004, v.16, 389-393, “Fabrication of Polyelectrolyte/Protein Microarrays Using a Laminar Flow Microfluidic Device”

  17. T. Shutava, V. John, Y. Lvov, Biomacromolecules, 2004, v.5, 914-921, “Microcapsule Modification with Peroxidase Catalyzed Phenol Polymerization”

  18. R. Ghan, T. Shutava, V. John, Y. Lvov, Macromolecules, 2004, v.37, 4519, “Enzyme Catalyzed Polymerization of Phenols within Polyelectrolyte Microcapsules”

  19. H. Ai, S. Jones, M. de Villiers, Y. Lvov, J. Controlled Release, 2003, v.86, 59-66, “Nanoencapsulation of Furosemide Microcrystals for Controlled Drug Release”

  20. F. Hua, J. Shi, Y. Lvov, T. Cui, Nanotechnology, 2003, v.14, 453-457, “Fabrication and Characterization of Capacitor Based on Layer-by-Layer Self-Assembled Thin Films”

  21. F. Hua, Y. Lvov, T. Cui, Nano Letters, 2002, v.2, 1219-1222, “Patterning of Layer-by-layer Self-assembled Multiple Types of Nanoparticle Thin Films by Lithographic Technique

  22. F. Hua, T. Cui, Y. Lvov, Langmuir, 2002, v.18, 6712-6715, “Lithographic Approach to Pattern Self-Assembled Polyelectrolyte Multilayers”

  23. M. McShane, J. Brown, K. Guice, Y. Lvov, J. Nanoscience and Nanotechnology, 2002, v.2, 411-416, “Polyelectrolyte Microshells as Carriers for Fluorescent Sensors: Loading and Sensing Properties of a Ruthenium-Based Oxygen Indicator”

  24. H. Ai, M. Fang, S. Jones, Y. Lvov, Biomacromolecules, 2002, v.3, 560-564 “Electrostatic Layer-by-Layer Nano-Assembly on Biological Microtemplates: Platelets”

  25. Y. Lvov, F. Caruso, Analytical Chemistry, 2001, v.73, 4212-4217, “Biocolloids with Ordered Urease Multilayer Shells as Enzymatic Reactors”

  26. Y. Lvov, A. Antipov, H. Möhwald, G. Sukhorukov, Nano Letters, 2001, v.1, 125-128, “Urease Encapsulation in Nano/organized Microshells”

  27. Y. Lvov, R. Price, A. Singh, J. Selinger, J. Schnur, Langmuir, 2000, v.16, 5932-5935, “Nanoscale Patterning on Biologically Derived Microstructures”

  28. Y. Lvov, J. Schenkman, J. Rusling, J. Am. Chemical Society, 1998, v.120, 4073-4080 “Direct Electrochemistry of Myoglobin and Cytochrome P450 in Alternate Layer-by-Layer Films with DNA and other Polyions”

  29. K. Ariga, Y. Lvov, T. Kunitake, J. Am. Chem. Soc., 1997, v.119, 2224-2231 "Assembling Alternate Dye-Polyion Molecular Films by Electrostatic Layer-by-Layer Adsorption"

  30. Y. Lvov, I. Ichinose, T. Kunitake, J. Am. Chem. Soc., 1995, v.117, 6117-6122 "Assembly of Multicomponent Protein Films by Means of Electrostatic Layer-by-Layer Adsorption"

 

  1. Books and chapters (published during last eight years)

Book edited:

"Protein Architecture: Interfacial Molecular Assembly and Immobilization Biotechnology", Editors: Y. Lvov and H. Möhwald, 2000, Marcel Dekker Publ., NY, pp. 1-394 (ISBN 0-8247-8236-4).

“Bio-Inorganic Nanostructured Hybrid Materials,” Editors: E. Ruiz-Hitzky, K. Ariga, and Y. Lvov, 2008 by Wiley Publ., London, Berlin, New York, pp. 1-520 (ISBN 978-3-527-31718-9) 

Twelve chapters in books

  1. Y. Lvov, R. Price, "Halloysite Nanotubules a Novel Substrate for the Controlled Delivery of Bioactive Molecules," in book: Bio-Inorganic Hybrid Nanomaterials, Editors: E. Ruiz-Hitzky, K. Ariga, Y. Lvov, Wiley Publ., London, Berlin, Ch 14, 454-480, 2008 (ISBN 978-3-527-31718-9)

  2. F. Hua, Y. Lvov, “Nanocomposites Fabricated by Layer-by-Layer Self-Assembly and Their Applications,” ch.1, in book: The New Frontiers of Organic and Composite Nanotechnology, Editor: Victor Erokhin, Elsevier Publ., 2007, pp 1-504 (ISBN 978-008-045052-0)

  3. H. Ai, Y. Lvov, “Biomaterials Based on Layer-by-Layer Nanoassembly: Ultrathin Coating and Microencapsulation,” in book: Bottom-Up Nanofabrication: Supramolecules, Self-Assemblies, and Organized Films. Editor: K. Ariga, 2007, American Scientific Publishers, NY, pp. 124-146.

  4. M. DeVilliers, Y. Lvov “Nanocapsules for Drug Delivery,” in book: "Nanotechnologies for Life Sciences," Editor: C. Kumar, v.10, Wiley-VCH, Berlin, Ch. 12, 527-556, 2006

  5. M. McShane, Y. Lvov, “Layer-by-Layer Electrostatic Self-Assembly for Biomaterials,” in book Encyclopedia of Nanoscience & Nanotechnology, Ed. J. Schwartz, C. Contescu, M. Dekker Publ., p.1-24, 2005, NY.

  6. T. Cui, Y. Lvov “Nanoassembly for Polymer Electronics,” in book Nanotechnology, Ed. H. Nalwa, 2004, Academic Press, NY, p.24-56.

  7. D. Shchukin, G. Sukhorukov, Y. Lvov, “Nanoengineered Inorganic / Organic Composite Microcapsules,” in book Micro- Nano Integration, Ed. H. Knobloch, 2004, Springer, Berlin-London, p. 213-224.

  8. K. Ariga, Y. Lvov “Self-Assembly of Functional Protein Multilayers: From Flat Films to Microtemplate Encapsulation”, in book: Biopolymers at Interfaces, Ed. M. Malmsten, M. Dekker Inc, 2003, NY, p.367-391.

  9. Ichinose, Y. Lvov, T. Kunitake “Recent Progress in the Surface Sol-Gel Process and Protein Multilayers”, in book: Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials. Eds. G. Decher, J. Schlenoff, J-M. Lehn, Wiley-VCH, 2003, p.245-262.

  10. Y. Lvov "Polyion / Protein Nanostructures," In book: Encyclopedia of Surface and Colloid Science, Ed. A. Hubbard, 2002, Marcel Dekker, NY, p. 4162-4171.

  11. Y. Lvov "Thin Film Nanofabrication by Alternate Adsorption of Polyions, Proteins and Nanoparticles," In book: Handbook for Surfaces and Interfaces, Volume 3: Nanostructured Materials, Ed: H. Nalwa, 2001, Academic Press, NY, p. 170-189.

  12. Y. Lvov, "Electrostatic Layer-by-Layer Assembly of Proteins and Polyions." In book: Protein Architecture: Interfacial Molecular Assembly and Immobilization Biotechnology, Ed: Y. Lvov and H. Möhwald, 2000, Marcel Dekker Publ., NY, p. 125-167.

 

Presentations with published abstracts Totally, more than 200 presentations.

Below, the titles of 15 major invited talks in the last eight years:

  1. Y. Lvov, “Nanoparticle / Polyion Assembly on Microtemplates (Lipid Tubules, Latex Spheres),” 9 LB-International Conference on Organized Molecular Films, 1 Sept 2000, Potsdam, Germany; Abstracts, p.60, – invited talk.

  2. Y. Lvov “Nano-Assembly by Alternate Adsorption,” American Chemical Society PolyMillennial-2000, International Conference, Hawaii, 9 Dec, 2000, Abstracts, p.195, - invited talk.

  3. Y. Lvov, Annual CAMD-School, Louisiana State University, Baton Rouge, June 12, 2001, “Organic Nanofilms,” Abstract, p.23. -invited lecture

  4. Y. Lvov, Gordon Conference on Organic Thin Films, Salve Regina, June 28, 2001, “Nanoassembly by Alternate Adsorption of Oppositely Charged Components” – invited talk.

  5. Y. Lvov, 223rd National American Chemical Society Meeting, Orlando, April 7-11, 2002, “Layer-by-Layer Polyion/Nanoparticle Assembly on 2D-Micropatterns and 3D-Microtemplates”- invited talk.

 

  1. Y. Lvov, “Novel Lithography-Based Approaches to Pattern Layer-by-Layer Self-Assembled Thin Films,” ASME International Mechanical Engineering Congress, 2002, Nov 17-22, New Orleans – invited talk.

  2. Y. Lvov, “Marriage” of LbL-Nanoassembly and Traditional Lithography for Microelectronics Element Production,” 226th National American Chemical Society Meeting, New York, September 9, 2003, Abstract #PMSE144 – invited talk.

  3. Y. Lvov, “Nanoengineered Microcapsule for Chemical Reaction in Confined Volume,” 78th American Chemical Society Colloid and Surface Science Meeting, New Haven, June 20, 2004 – invited talk.

  4. Y. Lvov, “Electrostatic Layer-by-Layer Nanoassembly: Films, Micropatterns, Cantilevers, Nanocapsules,” OpticsEast, SPIE Conference, Nanofabrication: Technology and Devices, Philadelphia, October 26, 2004 – invited talk

  5. Y. Lvov, “Pulp and Paper: Coating via Polyelectrolyte Nanoassembly and Synthesis in Microfiber’s Lumen,” 230th American Chemical Society National Meeting, Washington DC, August 28-September 1, 2005 – invited talk

  6. Y. Lvov, “Nano, Microencapsulation of Bioactive Macromolecules for Controlled Release Delivery (Nanoshells and Clay Nanotubules).” Micro/Nano-Encapsulation of Active Food Ingredients, 233rd American Chemical Society Meeting, Agriculture & Food Chemistry Division, April 1, 2007, Chicago – invited talk

  7. Y. Lvov, “Cellulose Microfiber Functionalizing through Nanocoating with Polyelectrolytes, Enzymes, and Nanoparticles,” 233rd American Chemical Society Meeting, Cellulose & Renewable Materials Division, April 1, 2007, Chicago – invited talk

  8. Y. Lvov, “Layer-by-Layer Nanocoating for Pharmaceuticals: from Microcapsules to Nanoshells,” 5th   International  Nanomedicine and Drug Delivery Symposium, Boston, November 2-3, 2007, - invited talk

  9. Y. Lvov, “1-, 2-, and 3-D Biomimetic Nanoassembly (Coating, Patterning and Encapsulation),” 8th World Biomaterials Congress, Layer-by-layer nanoassembled materials, 28 May 2008, Amsterdam - invited keynote speaker

  10. Y. Lvov, “Clay Nanotubes for Controlled Release of Protective Agents” Colloids Symposium in Memory of Janos Fendler, 236th National American Chemical Society Meeting, Aug 17-21, 2008, Philadelphia – invited talk

 

Invited lectures in universities and companies in the last eight years:

  1. Durham University, Center for Molecular Electronics, UK, “Nanoassembly via Alternate Adsorption of Oppositely Charged Components,” May 28, 2000. Host: Prof. M. Petty, Director of the Center.

  2. Max-Plank Institute for Colloids and Interfaces, Berlin, Germany, “Nano-Assembly on Microtemplates,” July 25, 2001. Host: Dr. F. Caruso.

  3. University of Texas, Medical Branch at Galveston, “Nanocapsules for Enzyme Delivery,” April 30, 2001. Host: Prof. J. Leary.

  4. Louisiana State University in Monroe, Pharmacology Department, “Nano-Assembly for Sustained Drug Release,” September 7, 2001 Host: Prof. K. Briski.

  5. Texas University in Arlington, Dallas, April 19, 2002 “Nanoassembly for Microcapsules,” Host: Prof. M. Pomerantz.

  6. Max-Plank Institute for Colloids and Interfaces, Berlin, July 12, 2002 “Micropatterning of Polyion / Nanoparticle Multilayers,” Host: Prof. H. Moehwald, Director of the Institute.

  7. Louisiana State University, Medical Branch in Shreveport, September 9, 2002 “Nanocapsule Technology,” Host: Prof. X. Qiao.

  8. T.J. Watson IBM Research Center, Yorktown Heights, NY, “Layer-by-Layer Self-Assembly: Organized Multilayers and Nanocapsules,” October 25, 2002, Host: Dr. C. Murray.

  9. Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington DC, “Nanocapsule Technology for Enzyme and Drug Encapsulation,” October 28, 2002, Host: Dr. J. Schnur, Director of Bio/Materials Engineering Center.

  10. Tulane University, Chemical Engineering Department, New Orleans, “Nanocapsules for Enzyme and Drug Delivery,” November 22, 2002 Host: Prof. V. John.

  11. Health Medical Center, Louisiana State University, New Orleans, “Layer-by-Layer Self-Assembly: 1) Organized Nanoshells for Enzyme and Drug Encapsulation; 2) Micropatterning and Micro/Nanoscale Biosensors,” January 31, 2003. Host: Prof. N. Bazan.

  12. CIBA-Vision Corporation, Division of Novartis, Duluth, GA, “Layer-by-Layer Assembly as a Method for Biocompatible Coating,” April 17, 2003, Host: Dr. G. White, Vice-President on Academic Connections.

  13. Cabot Corporation, Billerica, MA “Nanoparticle Enforced Polymer Composites,” September 11, 2003. Host: Dr. E. Step.

  14. Baxter Corporation, Boston, “Enzyme and Dye Nanoencapsulation and their Possible Applications,” September 12, 2003, Host: Dr. J. Rashba.

  15. International Paper Company, Cincinnati, “Applications of Layer-by-Layer Assembly for Paper Modification,” November 3, 2003, Host: Dr. N. Marsolan, Vice-President on Research.

  16. EPIC Therapeutic Incorporation, Norwood, MA, “Protein Encapsulation” May 7, 2004, Host: Dr. T. Scott

  17. Purdue University, Department of Biochemistry, IN, “Layer-by-Layer Self-Assembly: Organized Nanoshells for Enzyme and Drug Encapsulation. Micropatterning and Microfluidic for Cell Directing,” August 23, 2004. Host: Prof. A. Ivanisevic.

  18. New York Polytechnic University, Department of Chemistry and Chemical Engineering, Brooklyn Campus, “Biomimetic Synthesis in Polyelectrolyte Microcapsules,” September 10, 2004. Host: Prof. R. Gross

  19. Textile Research Institute (TRI-Princeton), Princeton, NJ, “Layer-by-Layer Assembly for Textile Applications,” October 28, 2004. Host: Dr. A. Neymark.

  20. Moscow State University, Chemistry Department, Russia, “Nanoassembly of Protein Arrays for Sensoric Microdevices,” November 30, 2004. Hosts: Prof. V. Levashov

  21. University of New Mexico, Department of Chemistry and Biochemistry, Albuquerque, “Protein Immobilization on Solid Surfaces,” February 8, 2005, Hosts: Prof. G. Lopes and P. Atanasso

  22. University of Minnesota, Minneapolis, ASME-Technology Seminar, Department of Electrical Engineering, “Polymer Nanoassembly,” April 18, 2005. Hosts: Prof. T. Cui and S. Bourke

  23. Virginia Tech, Chemical Engineering Department, Blacksburg, VA, “Layer-by-Layer Self-Assembly for Nanocoating,” April 25, 2005. Host: Prof. Rich Davis

  24. Parma University, Physics Department, Italy, Layer-by-Layer Nanoassembly: Applications for Encapsulation,” May 26, 2005, Host: Prof. Victor Erokhin

  25. Max Planck Institute for Colloids and Interfaces, Potsdam, Germany, “Pulp Fibers as Tubule Microtemplate for Layer-by-Layer Assembly and Interior Synthesis,” June 15, 2005. Host: Dmitry Shchukin

  26. Graphic Package Company, Monroe, LA, “Nanotechnology Pulp Processing for Stronger Paper,” October 11, 2005, host Vice-president on Research: Dr. Frank Palombo

  27. SAPPI Fine Paper Corporation, “Nanotechnology for Pulp and Paper Processing,” October 17, 2005, Westbrook, ME, host Dr. Dan Coughlin

  28. Weyerhaeuser Corporation, “Layer-by-Layer Polyelectrolyte Self-Assembly for Nanocoating and Encapsulation,” Seattle, WA, December 19, 2005; host: Dr. Pete Lancaster

  29. University of Wisconsin-Madison, School of Pharmacy, MD, “Nanoassembly for Drug Encapsulation,” April 21, 2006, host: Prof. Mel DeVilliers

  30. Moscow State University, Macromolecules and Polymer Science Department, Moscow, Russia, “Liposome Encapsulation for Sustain Drug Release,” June 4, 2006, host Prof. Alex Yaroslavov

  31. MIT, Materials Science and Engineering Dep., Cambridge, “Nanoparticle Self-Assembly as Smart Coating,” June 29, 2006, hosts: Profs. Michael Rubner and Robert Cohen

  32. Stevens Institute of Technology, Chemical Engineering Dep., Newark, “LbL Microencapsulation of Drugs:  Interpolyelectrolyte Complexation and Interior Protection,” July 3, 2006, host: Prof. Sveta Sukhishvili

  33. University of Maine, Portland, “Nanolayer Coating on Fibers and Other Materials,” Portland, July 13, Forest Product Industry Nanotechnology Research Interest Workshop organized by AF&PA Agenda-2020 Workgroup and facilitated by the University of Maine; hosts Drs. Phil Jones, and Jake Ward.

  34. Atlantis Mining Company, Nanoclay Technology Division, Eureka, UT, “Halloysite Nanotubules as Nanocontainer,” Sept 19, 2006. Host: Technical Director Mr. Ronald Price

  35. Cornell University, Department of Fiber Science, Ithaca, NY, “Layer-by-Layer Self-Assembly for Nanocoating on Microtemplates (fibers and capsules),” Oct 19, 2006, host: Prof. Juan Hinestroza

  36. Russian Academy of Sciences, Moscow, “Quantum Dot Nanoassembly – Multilayer System for Energy None/Emitting Transfer,” Lebedev’s Institute of Physics, Russian Academy of Sciences, Moscow, November 25, 2006; host: Head of Luminescence Laboratory, Prof. Alex Vitukhnovsky.

  37. Tyndall Air Force Base, Research Division, Panama City, “Nanoencapsulation of Bacteria,” April 2, 2007. Host: Dr. Glen Johnson

  38. Northeastern University, Boston, Cancer Nanomedicin Institute, “Polyelectrolyte Nanoshell for Drug Delivery,” April 16, 2007. Host: Director, Prof. Vlad Torchilin

  39. MeadWestvaco Center for Packaging Innovation NCSU Centennial Campus, Raleigh, NC 27606, North Caroline University, “Nanocoating for Smart Paper,” August 12, 2007, Host: Dr. Mark A Johnson,

  40. Cancer Hospital, Research Division and Louisiana State University Health Center, Shreveport, “Cancer Drug Nanocapsules,” August 16, 2007. Hosts: Prof. R. Toledo Gonzales, A. D’Augustino

  41. Max Planck Institute for Colloids and Interfaces, Potsdam, Germany, “Halloysite Nanotubules as Container for Controlled Release,” October 23, 2007. Host: Prof. Helmuth Moehwald

  42. Louis Paster Strasbourg University, Institute Charls Sadron, “Sustained Release from Clay Nanotubules and Drug Nanoparticles,” December 7, 2007. Host: Prof. Gero Decher

  43. University of Pittsburgh, School of Pharmacy, “Stable Nanocolloids of Poorly Soluble Drugs Using Layer-by-Layer Nanoassembly.” April 15, 2008. Host: Prof. David J. Edwards

 

Service

University Service

Co-chair of IfM-graduate bi-weekly seminar on Nanotechnology: “Functional Nanoassemblies: Fundamentals and Applications.” 112 reports were delivered on this seminar in the last five years.

Established LaTech collaboration with Max-Planck Institute for Colloids and Interfaces, Potsdam, Germany.  

Established collaboration with National Institute of Materials Science, Tsukuba, Japan

Member of Steering Committee for MS/PhD program in Molecular Chemistry and Nanotechnology, LaTech.

Member of Steering Committee for Governor Biotechnology Initiative program, LaTech.

Member of Inst for Micromanufacturing Leadership team.  

Professional Service

I was a panel referee for National Science Foundation panel on Nanoscale Centers, NSF Chemistry Program, NSF Ceramics Program, and NSF MRSEC program: 2004-2008; a referee for National Institute of Health (NIH) –2003-2007; American Chemical Society Petroleum Foundation - 15 reviews during 2000-2008, and for Army Research Office, Mechanical Sciences Division (2002-2006). Reviewer on Nanofiber Materials for US Army Research Office, 2006-2007 ● Reviewer for Congressionally Directed Medical Research Program, 2005-2006, projects on Targeted Nano-Therapeutics. ● Reviewer for US Civilian Research and Development Foundation on New Nanoparticle Materials, 2006-2008.

I was a Head of Organizing Committee of the American Chemical Society Symposium “Smart Nano-Assemblies,” New York Hilton Hotel, 7-10 Sept 2003. I was a chair of the 236th American Chemical Society Symposium “Nanoassembly: From Fundamental to Applications,” August 17-20, 2008, Philadelphia. There were ca 150 participants from US, Germany, France, UK, Japan, China, and Russia at this interesting and successful symposium.

In 2000-2008 I served as a peer referee for the following journals: Journal of American Chemical Society, Biomacromolecules, Langmuir, Macromolecules, Colloids and Surfaces: Engineering, J. Nanoscience and Nanotechnology, J. Physical Chemistry, Nano Letters, J. Colloid and Interface Sciences; J. Vacuum Science and Technology, Thin Solid Films, Analytical Chemistry, and Advanced Materials. More than 250 papers were reviewed for these prestigious international journals.  

Results dissemination:

● article in Ruston Daily Leader, July 18, 2008 “International journal features lauded professor: Work boosts cancer drugs.” ● article “Tech’s Lvov Named LA’s Top Researcher,” in The News Star, Monroe, October 25, 2006; ● paper “Professor Recognized as Outstanding Researcher,” in The Ruston Daily Leader, October 26, 2006 ● editorial article “Lvov’s Work no Small Feat,” in The News Star, Monroe, November 2, 2006; ● paper “Tech Nano-Researchers Pioneer Smarter, Tougher Paper,” in The News Star, Monroe, December 15, 2006; ● article “ULM-LaTech Join Research to Compete for Funding,” April 26, 2006 in The News-Star, Monroe;

National press: ● Cover page featuring of our drug nanocapsule research in journal “Pharma Focus Asia” July 2008 ● article: “Think Small – You Are Entering Nano-Zone. Nanotechnology for Forestry,” in PAPER-360º TAPPI National Journal, August issue of 2006, p.30-36, ● “Science-NASA” journal published a paper “Voyage to the Nano-Surgeons” describing our research on drug nanocapsule delivery, March 23, 2003.

 

Teaching:

New graduate course “Nanofabrication by Self-Assembly” was prepared and taught for six years with an overage enrollment of about 24 students. The following courses were taught at Louisiana Tech University during last 7 years with average enrollment of 60 students:

Undergraduate: General Physics, - PHYS 209 and 210; Physics for Engineers, - PHYS 201 and 202; Conceptual Physics,- PHYS 205 and 206.

Graduate: CHEM 523/450, and MSNT506 - “Nanofabrication by Self-Assembly,” MSE 505 - “Nanotechnology Principles,” MSE 501 - “Microsystem Principles” – part on nanoassembly; MSE 512 - “Biotechnology Principles” – part on bio/membranes, lipid mesophases, and Langmuir-Blodgett films; MSNT 504 – graduate nanotechnology seminar

Currently, I am a chair of advisory committee for 6 PhD grad students.

I was an advisor for five postdocs: Drs T. Shutova, Z. Lu, D. Schukin, G. Bantchev, M. Agarwal.

In last six years, the following my students graduated with a degree:

  1. Ms. Zhixuan Zhu, MS in Chemistry, 2001, “Layer-by-layer Self-assembly of Urease and Polycations”

  2. Ms. Jeanhong Qiu, MS in Chemistry, 2002, “Ultrathin Films of Arginase for Sensor Applications”

  3. Ms. Ming Fang, MS in Physics, 2002, “Magnetic Bio/Nanoreactor with Multilayer Shells of Glucose Oxidase and Inorganic Nanoparticles”

  4. Dr. Laura Pastorino, (co-chair with Victor Erokhin) PhD in Biophysics, LaTech/Genoa University, 2002, “Complex Catalytic Colloids on the Basis of Firefly Luciferase as Optical Nanosensor Platform”

  5. Dr. Hua Ai, PhD in Biomedical Engineering, 2002, “Biomedical Applications of Electrostatic Layer-by-Layer Nano-Assembly of Polymers, Enzymes and Nanoparticles”

  6. Mr. Sandeep Disawal, MS in Chemical Engineering, 2003 “Layer-by-Layer Immobilization of Organophosphorus Anhydrase”

  7. Dr. Feng Hua, PhD in Engineering, 2003, “Lithographic Approach to Pattern Self-assembled Polyelectrolyte Multilayers”

  8. Mr. Sachin Sah, MS in Biomedical Engineering, 2003,”Implementation of Microfluidic Device for Blood Platelet Analysis.”

  9. Dr. Jingshi Shi, PhD in Electrical Engineering, 2004, “Layer-by-layer Nanoassembly Combined with Microfabrication Techniques for Microelectronics and MEMS”

  10. Dr. Rohit Ghan, PhD in Engineering, 2004, “Biomimetic Synthesis within Polyelectrolyte Microcapsules: Characterization of Enzyme Catalyzed Polyphenols and Polypeptides”

  11. Dr. Amish Patel, PhD in Chemical Engineering, 2004 “ Layer-by-Layer Self-Assembly for Enzyme & DNA Encapsulation and Delivery“

  12. Dr. Zonghuan Lu, MS in Chemistry, 2004, “Nanoassembly of Polymeric Capsules Using MnCO3 Microcores as Template “

  13. Mr. Zhiguo Zheng, MS in Chemistry, 2005, “Nanoassembly for Pulp and Paper Processing”

  14. Dr. Dinesh Kommireddy, PhD in Engineering, 2005, “Biocompatible Nanocoating for Cell Tissue Engineering”

  15. Dr. Nikhil Pargaonkar, PhD in Biomedical Engineering, 2005, “Nanoengineered Microshells for Dexamethasone Sustained Release”

  16. Sandeep R. Eadula, MS in Nanotechnology and Molecular Biology, August 2006, “Nanocoating of Cellulose Microfibers for Novel Bioconjugates”

  17. Dr. Malcolm Prouty, PhD in Engineering, Aug 2007, “Layer-by-Layer Self-Assembly of Microcapsules for the Magnetic Activation of Semi-permeable Nanoshells.”

  18. Nalinkan G. Veerabadran, PhD in Biomedical Engineering, “Drug Encapsulation in Nanocapsules and Nanotubules,” August 2008

  19. Qi Xing, PhD in Engineering, expected in May 2009

  20. Shantanu Balkundi, PhD in Biomedical Engineering, expected in May 2009

  21. Anshul Agarwal, PhD in Biomedical Engineering, expected in May 2009.

  22. Zhiguo Zheng, PhD in Biomedical Engineering, expected Nov 2009

  23. Elshad Abdullaev, PhD in Engineering, expected Nov 2010

In earlier years of my career I was a chair for five students who graduated with PhD in physics and chemistry from the Institute of Crystallography, Russian Academy of Sciences (A. Krivandin, V. Erokhin, M. Vorobyev, M. Oimatov, and L. Valkova). Their works were devoted to the study of biological membranes, lipid mesophases, and to application of these systems in microelectronics using Langmuir-Blodgett assembly of nano/organized films. 

Industrial contracts: 2000- BioRad Corporation, California on magnetic nanocores; 2001-2003 contract with CIBA-Vision Corporation on eye lens biocompatible nanocoating; 2004-2007 contract with EPIC Therapeutics Inc, Baxter Corporation on insulin and other protein drug microencapsulation; 2006-2007 contract with SAPPI Fine Paper Corporation on nanotechnology for wood fiber processing, and 2007-2008 – contract with Atlas Mining Inc, UT on halloysite clay nanotubules.

Last 5 years collaboration: Naval Research Laboratory – A. Singh and J. Schnur; University of Connecticut – J. Rusling; S. Suib; Max Planck Institute for Colloids and Interfaces, Germany - H. Moehwald, D. Shchukin; Queen Mary College, London University, - G. Sukhorukov; and National Institute of Materials Sciences, Tsukuba, Japan - I. Ichinose, K. Ariga 

Additional Information

 

My Advisors: PhD - Lev Feigin (Russian Academy of Sciences, Moscow); postdoctoral - Helmuth Moehwald (Max Planck Institute for Colloids and Interfaces, Germany), and Toyoki Kunitake (Kyushu University and, currently, Tsukuba Research Center, Japan).