The Bio-nanomaterials Interface Design & Applications Laboratory (BIDAL) is directed by Dr. Adarsh Radadia at Louisiana Tech University. The work at BIDAL aims to build novel micro- and nano fabricated sensors to interface with biology at various scales and address challenges in diagnostics, therapeutics, bioelectronics, and fundamental biology. This includes developing novel schemes combining on-chip sample preparation, pre-concentration and orthogonal detection. Current tools lack the ideal biology-materials interface that is chemically and mechanically suitable for such applications. Surface of carbon nanomaterials promise such a stable interface. Research at BIDAL focuses on development of biosensors with carbon nanomaterials, surface chemistries to tether biomolecules to carbon nanomaterials, and study the stability and interactions of biomolecules at such interfaces. Nano-diamond and graphene are the carbon nano materials of specific interest. These nanoscale interface are designed and characterized using techniques in surface chemistry, micro and nanofabrication, and materials characterization.
Nanodiamond and diamond thin film based biosensors and its surface chemistry
Graphene film based biosensors and its surface chemistry
- Zhang, W.; Tullier, M. P.; Patel, K.; Carranza, A.; Pojman, J. A.; Radadia, A. D., Microfluidics using a thiol-acrylate resin for fluorescence-based pathogen detection assays. Lab on a chip 2015.
- Zhang, W.; Patel, K.; Schexnider, A.; Banu, S.; Radadia, A. D., Nanostructuring of biosensing electrodes with nanodiamonds for antibody immobilization. ACS nano 2014, 8 (2), 1419-28.
- Radadia A.D.*, Stavis C.J., Carr R., Zeng H., King W.P., Carlisle J.A., Aksimentiev A., Hamers R.J., Bashir R., Control of nanoscale environment to improve stability of immobilized proteins on diamond surfaces, Advanced Functional Materials 21-6 (2011) pp. 1040-1050. *Cover Article