Preliminary Report for Project Proposal
1. Project summary:
a. What is the primary problem that you intend to address?
b. What specific aspect of this problem will you address?
c. How will you address this problem?
d. What will be the benefits of your design?
2. Specific Aims:
a) What general clinical problem are you addressing?
b) What are the financial and sociological consequences of this disease?
c) How many
people suffer from this disease? (Be
specific as to whether you are talking about 2% of people in
d) What aspect of the disease has not been addressed clinically (should directly relate to f) below)?
e) What new technology, news event, sociological change, or other phenomenon makes it feasible or desirable to address this aspect now?
f) What do you specifically propose to do to help treat, diagnose, cure or reduce the consequences of the disease?
3. Background and Significance:
a. Background: Describe the problem you intend to address in terms that any of your colleagues (seniors in BIEN 400) can understand. Your description will include such things as:
a. What system of systems in the body are affected?
b. What subgroup(s) of people are subject to this disease?
c. What is known about the underlying cause of the disease?
b. What new technologies have arisen in the past 5 years that could be applied to the problem of interest? Do not just list new technologies. You must have some idea in mind as to how those technologies could be applied to the problem.
c. Analysis of Need: What are the needs of individuals with this specific problem? These needs may include ways to make the patient more comfortable, ways to cure the pathology, ways to keep the pathology from getting worse, ways to help the person lead a “normal” life, etc. How are these needs currently being met? For each of these “solutions,” state why it is not complete. How could it be improved. Of these, select one that you feel has not been addressed adequately.
d. Current Solutions: Provide 5 commercially available devices that address the aspect identified above (i.e., the one aspect of the problem that is not being met and that you think you can improve on). What approaches and technologies have not yet been applied to the specific problem?
e. Problem to be Solved: State in a couple of sentences the specific aspect of the problem you will address and the main approach you will take.
f. Design Criteria:
i. Provide at least 5 criteria that you consider to constitute a solution to the problem.
ii. For each criteria, what measurement can you make to verify that your device satisfies the criterion?
iii. What range of values for each measurement would be acceptable enough for your device?
iv. Rank each criterion according to its importance.
g. Analysis of alternative solutions: Give three different designs that could satisfy the design criteria specified above. State which one you consider to be the best and why.Do not just list new technologies. You must have some idea in mind as to how those technologies could be applied to the problem.
8. Preliminary Results: Provide a description of a simple experiement that is related to the design you wish to make. This can be a simple experiment that makes use of common household items.
9. Research Plan:
a. Detailed design:
i. Draw a sketch of what you expect your device to look like. Carefully label all parts.
ii. Outline a quantitative analysis that can describe the interaction of this device with the human body.
b. Cost Analysis: Give an estimate of the cost of building a prototype.
c. Method of evaluation: How will you evaluate each of the design criteria that you outlined in 7e above? I.e. sketch a device that you can use to make the measurement, or provide a block diagram for the measurement.
d. Ghantt Chart: Give a time table of specific landmarks in your design. Do not make this general (e.g. project definition, evaluation of solution, etc.), but be specific about your project.
10. Conclusion: What do you expect to conclude from your analysis?
11. Acknowledgements: Name 5 people outside of this class that you have consulted with or will consult with in your design process. State how each one will help you.
12. References: Provide 20 refereed articles that you have used in the examination of this project.